(AP) -- Kyle O'Quinn had 26 points and 14 rebounds, making several key plays in the closing minutes, and the gritty No. 15 seed Spartans held on through a tense final minute to topple second-seeded Missouri 86-84 on Friday in the West Regional.
Pendarvis Williams and Chris McEachin each added 20 points for the MEAC champion Spartans (26-9), who made their first trip to the NCAA tournament a memorable one.
They became the fifth No. 15 seed to beat a No. 2 and the first since fellow conference member Hampton in 2001.
O'Quinn had a chance to take some of the drama out of the finish when he went to the free throw line with 3.8 seconds to go, but the 70-percent foul shooter missed both tries.
Missouri coach Frank Haith called a timeout with 2.9 seconds left to set up a final play, and the ball wound up in the hands of Phil Pressey.
He took a couple of hard dribbles and let loose a 3-pointer from the wing that clanked off the back iron as the buzzer sounded.
Michael Dixon led Missouri (30-5) with 22 points, and Pressey and fellow guard Marcus Denmon finished with 20 points each. Pressey also contributed eight assists.
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