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(AP) -- Freshman swingman Le'Bryan Nash scored a career-high 27 points, Brian Williams added a career-best 22 and Oklahoma State knocked off No. 2 Missouri 79-72 on Wednesday night.

Nash, a McDonald's All-American, scored 13 points during a 17-4 burst that sent the Cowboys into the lead in the final 4 minutes and the Tigers (18-2, 5-2 Big 12) didn't have a response.

Nash hit a jumper and a 3-pointer to get it going, then nailed another 3 from the left side to give the Cowboys (10-10, 3-4) a 65-64 lead with 3:23 to play.

He connected on another 29 seconds later and ran to the opposite end of the court when Missouri called timeout to encourage a student section that was already hopping up and down to bring it on.

Ricardo Ratliffe had 25 points and 12 rebounds to lead Missouri.

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