KEOSAUQUA, IOWA -- Two tragic incidents connected with an annual motorcycle rally leaves two Iowans dead.

Midwest bikers are gathering in Keosauqua for the annual "State Line Motorcycle Rally."

While things were calm and quiet Saturday, the weekend began with tragedy.

Late Thursday a Fairfield woman lost her life after being thrown from a motorcycle.

The Iowa State Patrol reports that 50-year-old Colleen Smith was riding with her husband, Harold, on Highway 1 at around 7:30.

A deer ran into traffic and Harold swerved to avoid an accident.

The pair landed in a nearby ditch and Colleen Smith later died.

Then on Friday, a separate incident caused the death of a Lockridge man.

The Van Buren County Sheriff's office received a call of an unresponsive man at the camp site at around 3 p.m.

Officials found 53-year-old Jerry Pohren dead inside a vehicle when they arrived.

Dave Lyon, with the rally, told KTVO that Pohren and two others started up an old bus, which filled with fumes.

Sheriff’s officials said the two other men were taken to Iowa City Hospitals with symptoms of carbon monoxide poisoning.

Authorities are awaiting the results of an autopsy before making an official determination of Pohren's cause of death.